https://nova.newcastle.edu.au/vital/access/ /manager/Index ${session.getAttribute("locale")} 5 Genome-wide association study of retinopathy in individuals without diabetes https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:15067 Wed 11 Apr 2018 16:52:00 AEST ]]> Genetic loci for retinal arteriolar microcirculation https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:15066 Wed 11 Apr 2018 14:58:51 AEST ]]> Insights into the genetic architecture of early stage age-related macular degeneration: a genome-wide association study meta-analysis https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:15068 Wed 11 Apr 2018 13:50:10 AEST ]]> Carbohydrate nutrition is associated with changes in the retinal vascular structure and branching pattern in children https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:16926 Sat 24 Mar 2018 08:00:29 AEDT ]]> Genetic association of refractive error and axial length with 15q14 but not 15q25 in the Blue Mountains Eye Study Cohort https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:28445 −2 at rs685352 to 6.4x10−4 at rs560764, whereas association could not be confirmed for SNPs at the 15q25 locus, with P values ranging from 8.0x10−1 to 6.4x10−1. Ocular biometric analysis revealed that axial length was the most likely trait underlying the refractive error association at the 15q14 locus for SNPs rs560766 (P =0.0054), rs634990 (P =0.0086), and rs8032019 (P =0.0081). Conclusions: Our results confirm the association with refractive error at the 15q14 locus but do not support the association observed at the 15q25 locus. Axial length seemed to be a major parameter at the 15q14 locus, underscoring the importance of this locus in myopia and future clinical treatment. Financial Disclosure(s): The author(s) have no proprietary or commercial interest in any materials discussed in this article.]]> Sat 24 Mar 2018 07:29:01 AEDT ]]> Meta-analysis of genome-wide association studies in five cohorts reveals common variants in RBFOX1, a regulator of tissue-specific splicing, associated with refractive error https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:28356 −9) in a combined discovery and replication set (26 953 samples). This single nucleotide polymorphism (SNP) is located within the RBFOX1 gene which is a neuron-specific splicing factor regulating a wide range of alternative splicing events implicated in neuronal development and maturation, including transcription factors, other splicing factors and synaptic proteins.]]> Sat 24 Mar 2018 07:25:12 AEDT ]]> Exploring Factors Underlying Ethnic Difference in Age-related Macular Degeneration Prevalence https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:49503 Fri 19 May 2023 12:58:08 AEST ]]>